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filter countData by gene expression, perform cpm and log2(cpm+1) transformation

Usage

filter_calcpm_dge(count_df, group = NULL, min_count = 10, min_prop = 0.1)

Arguments

count_df

a data.frame of count data, rows are genes and columns are samples

group

a vector of group information, default is NULL, every sample is in the same group

min_count

minimum count for a gene to be kept, default is 10

min_prop

minimum proportion of samples in the smallest group to have the minimum count, default is 0.1

Value

a list of edgeR objects, including dge_count, dge_cpm, dge_keep, dge_keep_cpm, dge_keep_cpm_log

Examples

filter_calcpm_dge(count_df)
#> Warning: All samples appear to belong to the same group.
#> $dge_count
#> An object of class "DGEList"
#> $counts
#>        sample_1 sample_2 sample_3 sample_4 sample_5 sample_6 sample_7 sample_8
#> gene_1      110      107       90       99      112       85       91      109
#> gene_2      104      111       98      109      109      122      121       71
#> gene_3      102      111       90      109      118      114      101       92
#> gene_4       88       93      103       99       96       77       98       99
#> gene_5      111      105       92      103      109      104       95      110
#>        sample_9 sample_10 sample_11 sample_12 sample_13 sample_14 sample_15
#> gene_1      101       106       105       114        78        94        96
#> gene_2      108       108        93        83       125        97       116
#> gene_3      100        92       106       111        83       115       103
#> gene_4       83        94        94       108        90       105       100
#> gene_5       91       104        90        99        97       111        81
#>        sample_16 sample_17 sample_18 sample_19 sample_20
#> gene_1       105        91       108        88       109
#> gene_2       104       102       106        83       115
#> gene_3        80       102        98        85       119
#> gene_4        98       116        91        89        98
#> gene_5       103       113       102       109       107
#> 95 more rows ...
#> 
#> $samples
#>          group lib.size norm.factors
#> sample_1     1    10135            1
#> sample_2     1    10135            1
#> sample_3     1    10129            1
#> sample_4     1     9857            1
#> sample_5     1    10056            1
#> 15 more rows ...
#> 
#> 
#> $dge_cpm
#>           sample_1  sample_2  sample_3  sample_4  sample_5  sample_6  sample_7
#> gene_1   10853.478 10557.474  8885.379 10043.624 11137.629  8396.720  9117.323
#> gene_2   10261.470 10952.146  9675.190 11058.131 10839.300 12051.763 12123.034
#> gene_3   10064.134 10952.146  8885.379 11058.131 11734.288 11261.484 10119.227
#> gene_4    8682.782  9176.122 10168.822 10043.624  9546.539  7606.441  9818.655
#> gene_5   10952.146 10360.138  9082.831 10449.427 10839.300 10273.634  9518.084
#> gene_6    9176.122  8584.114 11353.539  9130.567 12132.060  9483.355  9217.513
#> gene_7    9373.458  9768.130  7898.114  9434.919  9248.210 10866.344 10519.988
#> gene_8    8584.114 10754.810  9576.464  9942.173 10143.198  9878.495  9918.846
#> gene_9    8288.111  9373.458 10168.822  9232.018  9944.312 10076.064  8315.800
#> gene_10  10853.478  8978.786  9379.011 11058.131 10043.755  9088.215 10119.227
#> gene_11  10162.802  8584.114 10859.907 10449.427 10043.755  9680.925 10720.369
#> gene_12   8682.782  9669.462  8293.020  9333.469  8850.438 10372.419  9417.894
#> gene_13   9472.126  9077.454  8984.105  9637.821 10441.527  9878.495  8616.371
#> gene_14   8584.114 10458.806 10958.634  9536.370  8651.551 10471.204  9618.275
#> gene_15   8978.786  9274.790  8786.652  8217.510 10441.527  9483.355 10419.798
#> gene_16  10064.134  9768.130  8490.473  8826.215 12132.060 10076.064 12323.414
#> gene_17   9669.462  9176.122 11254.813 10753.779 10242.641  9779.710  9417.894
#> gene_18  10656.142  9274.790 12735.709  9942.173 10143.198  8989.430 10519.988
#> gene_19  12136.162  9274.790  9181.558  9434.919 10839.300 11557.839  8215.610
#> gene_20  10754.810  9965.466  9477.737  9333.469  9944.312  9285.785  9618.275
#> gene_21  11248.150  7893.439 10465.001 10145.075 10242.641 10372.419  9317.704
#> gene_22   9669.462 11050.814  8490.473 11362.484 10640.414  8693.075  8315.800
#> gene_23  11544.154 10162.802  8293.020 11666.836  9944.312  9384.570 10219.417
#> gene_24   9077.454 11149.482  8293.020  9739.272  9347.653  8594.290  9417.894
#> gene_25   8386.778 10064.134  9872.643  9536.370  9248.210  9187.000  8816.752
#> gene_26  10261.470  9768.130 10465.001 10145.075  9347.653  8989.430 10319.607
#> gene_27  11544.154  9866.798  9576.464  9232.018 10839.300  9779.710  9618.275
#> gene_28   8978.786 10162.802  9773.916 10652.328 10342.084 10372.419  8315.800
#> gene_29  10853.478 10162.802 10563.728 12579.892 11634.845  8791.860 11421.701
#> gene_30   8978.786  9866.798  9773.916  9942.173 12728.719  9779.710 10519.988
#> gene_31   9472.126 10656.142 10859.907  9333.469 10242.641 10076.064 11822.463
#> gene_32  10656.142 11346.818 11156.086  9130.567 11237.072 10767.559 10820.559
#> gene_33   8880.118  9472.126  9872.643 12072.639  9148.767  9977.279 10319.607
#> gene_34  10360.138  8288.111  9280.284  9942.173 10043.755 10569.989 10419.798
#> gene_35   9866.798 10557.474 10662.454 10956.681 10441.527  8791.860 10720.369
#> gene_36   8781.450 11149.482  9181.558 11261.033  8850.438  8791.860 11020.940
#> gene_37  10162.802 10162.802  9773.916  9536.370 10242.641  8791.860  9317.704
#> gene_38  10853.478 11445.486  9379.011 10347.976 10640.414 10767.559 10920.749
#> gene_39  12136.162  9373.458 12735.709  9840.722  9049.324  9187.000  9117.323
#> gene_40  11248.150 10557.474  9477.737 11261.033  9944.312  9187.000 10219.417
#> gene_41   9274.790  8090.775  7996.841  9942.173  9447.096  8890.645  9718.465
#> gene_42  11840.158 10360.138 11945.898  8724.764  9347.653  9483.355  9818.655
#> gene_43   7400.099 10754.810 10070.096  8623.313  9645.982  9187.000  9417.894
#> gene_44   9472.126  8584.114  9675.190  9029.116  9844.869 10767.559  9217.513
#> gene_45   9472.126  9669.462  7996.841  9333.469 10043.755  9088.215  9518.084
#> gene_46   8288.111 10064.134  8885.379 10956.681 10839.300 10076.064 10419.798
#> gene_47  11149.482  9472.126 10267.549  9434.919 10143.198 10471.204 10720.369
#> gene_48  11149.482 10458.806  9379.011 10043.624 10839.300  8495.505 10920.749
#> gene_49  10064.134 11050.814  9773.916  9739.272 12927.605  9977.279  9518.084
#> gene_50   9768.130  9965.466 10267.549 11666.836 11535.402  9878.495 10119.227
#> gene_51   9176.122  9274.790 10465.001 10246.525  9645.982  8791.860 10119.227
#> gene_52  10853.478 11248.150  9773.916 10347.976  9546.539  8693.075 11822.463
#> gene_53  10360.138 10754.810 10859.907 10956.681 10342.084 10471.204  8215.610
#> gene_54   9373.458 10458.806  9773.916 12681.343  9447.096 10767.559  8816.752
#> gene_55  10458.806  8090.775  8490.473  8014.609 10739.857  9878.495 10820.559
#> gene_56  11346.818  9866.798 10958.634  8217.510  8949.881  8297.935 10319.607
#> gene_57  10458.806 10458.806  8687.926 10246.525  9546.539 11261.484 11421.701
#> gene_58   9965.466  9965.466 10267.549  9232.018 10739.857 10767.559 10119.227
#> gene_59   9768.130 10952.146 11550.992  9434.919 10143.198  9187.000 10419.798
#> gene_60  11840.158 12925.506 10070.096 10652.328 11734.288 10668.774  9718.465
#> gene_61  10853.478 11149.482 10958.634  8521.863  9546.539 11952.978  8816.752
#> gene_62   8781.450  8781.450  8885.379 10550.878 10839.300  9977.279  9618.275
#> gene_63   9472.126 10458.806 10168.822  9232.018 10839.300 10866.344  9618.275
#> gene_64   9669.462  8978.786 10070.096 10246.525 11137.629  9088.215  8315.800
#> gene_65   9373.458 10557.474 10563.728  9637.821  8750.994  9878.495 10620.178
#> gene_66   9965.466 12136.162 12242.077 11463.934 10441.527 10174.849  8516.181
#> gene_67   9274.790  9077.454 10070.096  9232.018 10640.414 10076.064 11421.701
#> gene_68  10162.802 10162.802  9675.190 11463.934  8949.881 11261.484 10720.369
#> gene_69  11544.154 10557.474 10662.454 11159.582  8750.994  9977.279 12423.605
#> gene_70   8978.786  9965.466 10267.549 10449.427  9844.869 10174.849 10019.036
#> gene_71   9472.126 11741.490  9280.284 10043.624 10739.857 12743.258  9918.846
#> gene_72  10853.478  9669.462  9181.558  8014.609  8949.881 10372.419 11622.082
#> gene_73   9965.466  9866.798 12834.436 10043.624  9447.096 11360.269 11822.463
#> gene_74   9274.790  9866.798  9872.643 10043.624  8353.222 10174.849 10019.036
#> gene_75  10853.478 10458.806 11452.266 10652.328  8949.881 10965.129 10920.749
#> gene_76  11248.150  8880.118 10761.181 10449.427 10739.857 10273.634 10419.798
#> gene_77   9768.130  9768.130 12538.256  9130.567  9645.982 10273.634 10319.607
#> gene_78  10162.802 10754.810  9280.284 10956.681  9944.312 10668.774 10119.227
#> gene_79   9768.130  9176.122 10070.096  9942.173  8651.551  9878.495  9918.846
#> gene_80  10853.478  9866.798  9872.643  9029.116  9745.426 10866.344  8215.610
#> gene_81   8781.450  9274.790 12044.624  9739.272  9049.324  8989.430  8916.942
#> gene_82  11840.158  9472.126 10662.454  8420.412 11933.174 10569.989  9017.133
#> gene_83   9077.454  9570.794 10662.454 10145.075  9447.096  7408.871 11321.511
#> gene_84  12234.830  9965.466 10859.907 10753.779  9148.767 12051.763  9417.894
#> gene_85  10458.806  9373.458  9675.190 10043.624  8850.438 11063.914 10019.036
#> gene_86   8880.118  9077.454  9872.643 10043.624  8651.551 10273.634 12223.224
#> gene_87   8682.782  9768.130  9181.558  9840.722  9148.767 10076.064  9718.465
#> gene_88   9965.466  9274.790  9280.284 11261.033 10441.527 11063.914  9217.513
#> gene_89   9965.466  9472.126 10070.096  8014.609  8750.994  8594.290 10319.607
#> gene_90   9472.126 10458.806 11254.813  9434.919 10143.198  9878.495 10219.417
#> gene_91   9176.122 10458.806 10761.181  7405.904  7557.677 12446.903  9017.133
#> gene_92   9669.462 10557.474 10761.181 10145.075  9745.426 11854.193 10219.417
#> gene_93  10162.802 10360.138  9280.284 10753.779  9049.324 10767.559  9417.894
#> gene_94  10064.134 11149.482  9971.369  9942.173  9248.210  9582.140  9518.084
#> gene_95  10064.134 10557.474  9181.558  9536.370  9944.312  8396.720  9417.894
#> gene_96  11149.482  9768.130 10563.728  8724.764 10242.641  9878.495 11121.130
#> gene_97   9669.462  9077.454  9773.916 10145.075  8452.665  9088.215  9518.084
#> gene_98  10261.470 10853.478  9280.284  9637.821  8949.881 10076.064  8616.371
#> gene_99  10754.810  9373.458 10168.822  9637.821 10640.414 10471.204 10419.798
#> gene_100  8682.782 10656.142  8786.652 12985.695  8750.994 11952.978  9117.323
#>          sample_8  sample_9 sample_10 sample_11 sample_12 sample_13 sample_14
#> gene_1   10898.91  9867.136 10536.779 10615.711 11379.517  7834.472  9294.048
#> gene_2    7099.29 10550.996 10735.586  9402.487  8285.087 12555.243  9590.666
#> gene_3    9199.08  9769.441  9145.129 10716.813 11080.056  8336.681 11370.378
#> gene_4    9899.01  8108.636  9343.936  9503.589 10780.595  9039.775 10381.649
#> gene_5   10998.90  8890.191 10337.972  9099.181  9882.212  9742.869 10974.886
#> gene_6   10398.96 10844.080  9840.954 10110.201 10381.314 12655.685  9392.921
#> gene_7    8999.10  9085.580  8846.918  8896.977 12178.079  8939.333 10480.522
#> gene_8   11598.84  8401.719  8648.111 10009.099  8884.009 10445.962  9887.285
#> gene_9    9899.01 10062.524 11033.797 11323.425 12876.822  9341.101  9590.666
#> gene_10  10398.96  8597.108  9145.129  9907.997 11878.618  8437.123  9689.539
#> gene_11  10498.95  8792.497 10238.569 11424.527  8484.727 11751.708  8503.065
#> gene_12  10598.94 10355.608  9244.533 11222.323  9283.290  8236.239 10678.268
#> gene_13   9099.09 11527.941  9045.726 10211.303 10481.134 10546.404 10381.649
#> gene_14  10198.98  9476.358  9642.147 11020.119  9383.110 10445.962 11666.996
#> gene_15   9599.04 10844.080 11332.008  8189.263 10381.314 10044.194 10282.776
#> gene_16  10598.94 11723.329 10735.586 10009.099 10381.314 10144.636  9788.412
#> gene_17   8599.14 11234.857  9542.744  9200.283  9882.212  9843.311  9294.048
#> gene_18  10198.98 10160.219  8946.322 10110.201  8384.907  9240.659  9788.412
#> gene_19   9599.04 10550.996 11630.219 11020.119 11579.158 10646.846 11864.742
#> gene_20   8899.11 10648.691  9642.147  9806.895  8584.548 10646.846  9294.048
#> gene_21   9699.03  9378.664  9244.533 11626.731  9083.649  9140.217 10381.649
#> gene_22   8799.12  8987.886  8648.111  9099.181  9582.751  9341.101  9096.302
#> gene_23   9699.03  9085.580 11332.008 10615.711  9482.931  8336.681  8799.684
#> gene_24   8799.12  9378.664 11133.201  9503.589 10481.134  9341.101  9986.158
#> gene_25  10398.96 10062.524 10437.376 11323.425  7885.806 11249.498  9294.048
#> gene_26  10098.99 10453.302  8747.515 10615.711 10580.954 10445.962  9986.158
#> gene_27  10698.93  9085.580 10139.165  9503.589  9283.290 10144.636 10282.776
#> gene_28   9999.00  8597.108 10238.569  9705.793 10181.673  9039.775  9392.921
#> gene_29   9899.01  8010.942  9145.129 10211.303  8784.188  9943.753 10777.141
#> gene_30  10698.93  7815.553  9542.744 10110.201  9782.392 10245.078 10876.013
#> gene_31   8899.11  9769.441  9542.744  9503.589 10081.853  8939.333  8898.556
#> gene_32  10398.96 10257.913  9045.726  8795.875  9782.392 10948.172  8997.429
#> gene_33   9099.09  9769.441 10139.165  9604.691 10181.673 10445.962  9689.539
#> gene_34  10098.99  9671.747 10139.165  8593.671 12277.900  8537.565  9195.175
#> gene_35   8899.11 10941.774 10934.394 12031.139 10780.595  8537.565 10183.904
#> gene_36  10498.95  9574.052 11630.219 10919.017  9283.290 10646.846  9096.302
#> gene_37  11198.88  7620.164  9045.726  9604.691 11279.697  7734.030 11963.615
#> gene_38  10798.92 11527.941  7952.286 10919.017 10980.236 11751.708  9294.048
#> gene_39  10298.97  9574.052  9642.147 11323.425  9682.571 10847.730 11469.251
#> gene_40   9999.00 10746.385  9940.358  9402.487 10680.775 11550.824  9096.302
#> gene_41   9899.01 10355.608  8548.708 10211.303 10580.954 10245.078 10480.522
#> gene_42   9299.07  9183.275 10636.183 10514.609  9083.649 10345.520 11073.759
#> gene_43   9099.09  8792.497 10139.165 12637.751  8784.188 12053.033  7810.955
#> gene_44   9799.02 11430.246 11530.815 10211.303  9582.751 10546.404 12359.106
#> gene_45   9399.06 11527.941  9840.954 10817.915  8285.087  9843.311  8503.065
#> gene_46   9899.01 11332.552 10536.779 10413.507 10081.853 10646.846 11172.632
#> gene_47   9299.07 11234.857 10536.779 10009.099 11479.337 10044.194 10282.776
#> gene_48   9799.02  9574.052 10337.972  9705.793  9782.392 10445.962  9887.285
#> gene_49   9899.01 12114.107  9244.533  8795.875  8884.009 10345.520  8305.319
#> gene_50  11798.82  8694.803 10139.165 11525.629 10580.954 10546.404  9887.285
#> gene_51  10298.97  9867.136  8946.322 10919.017 13076.462 10747.288  7316.591
#> gene_52   8799.12  9867.136 10238.569  8088.161 10481.134  8738.449 10876.013
#> gene_53  10498.95 10941.774 10934.394  8998.079 11179.876 10646.846 10282.776
#> gene_54  10598.94 10257.913 11133.201  8290.365  9482.931 10546.404  9096.302
#> gene_55   9399.06  8890.191  9840.954 11020.119  9283.290  9541.985 10183.904
#> gene_56   8599.14 10453.302 10536.779 12637.751  8983.829 11751.708 11963.615
#> gene_57  10698.93 10746.385  9940.358 10716.813  9682.571  9642.427  9788.412
#> gene_58   9899.01  9964.830 10039.761  9200.283  9582.751  9441.543 10876.013
#> gene_59   9899.01 11625.635 11530.815 10312.405 10680.775 10144.636  9590.666
#> gene_60  11798.82 10160.219 11729.622 11525.629 10880.415  9541.985  9788.412
#> gene_61  10098.99 10453.302  8548.708  9301.385  8285.087 10044.194  9986.158
#> gene_62   9799.02  9867.136  9045.726 10919.017 10980.236  8437.123 11370.378
#> gene_63  10798.92  9769.441  9343.936 10615.711 10680.775 10144.636  9096.302
#> gene_64  10198.98  9183.275  9741.551  8998.079  8983.829 10445.962  9392.921
#> gene_65  10398.96 10062.524  8250.497  9503.589 10481.134  8236.239  9590.666
#> gene_66  11098.89  9280.969  9940.358  8088.161 11878.618 11550.824 11469.251
#> gene_67  10998.90  9964.830 12226.640  9806.895  9482.931 10847.730 10282.776
#> gene_68  11398.86  9671.747  8548.708 10615.711 11878.618 12053.033 10085.031
#> gene_69  10198.98  9964.830 10039.761  9907.997  9682.571 12354.359 10183.904
#> gene_70  10298.97  9085.580 10238.569 11323.425 10880.415  8537.565 10282.776
#> gene_71   8399.16 10257.913  9443.340 10312.405  9482.931  9541.985 10678.268
#> gene_72   9999.00 12016.413  9542.744 10110.201  9882.212  9742.869  9096.302
#> gene_73   9899.01  8890.191 10934.394  9503.589 10780.595  9541.985 11864.742
#> gene_74   8699.13  8792.497 11332.008  9806.895  9383.110 10245.078 11666.996
#> gene_75   9199.08 10844.080  8846.918 10919.017  7885.806  9341.101  9294.048
#> gene_76  11698.83 10453.302 10834.990  8593.671  9383.110  9039.775 11864.742
#> gene_77   9099.09  9085.580 10238.569 10716.813 10181.673  9943.753  8997.429
#> gene_78   9899.01  9769.441 10039.761  9604.691  9383.110  9039.775  9590.666
#> gene_79   8999.10  8890.191  9642.147  9402.487  9183.470  9742.869  9195.175
#> gene_80  10598.94  9964.830  8449.304  9907.997 10780.595  9742.869  9986.158
#> gene_81  11098.89 10257.913 10934.394 10615.711  9882.212 10546.404  8008.701
#> gene_82  10598.94 10257.913 11232.604  8694.773 10281.493 10747.288  9788.412
#> gene_83  11898.81 11625.635  9244.533  9402.487  8784.188  9240.659 10777.141
#> gene_84   9499.05 10453.302 11332.008  7784.855  9383.110 10546.404 10777.141
#> gene_85   8699.13 10355.608  9840.954  9099.181 10381.314 11550.824  9392.921
#> gene_86  10498.95  9476.358 12226.640  9301.385 10481.134 10044.194 10282.776
#> gene_87  11698.83  9671.747 10437.376  9402.487 10181.673  9140.217 10480.522
#> gene_88   8099.19  9574.052 12027.833  8795.875 10481.134  9240.659 10381.649
#> gene_89  11298.87  9964.830 11133.201 10413.507 11379.517  9742.869 11073.759
#> gene_90  11098.89  9476.358  9443.340  8896.977 11379.517 10144.636 11073.759
#> gene_91  11698.83  8890.191  9840.954  9301.385  9982.032  9642.427  9392.921
#> gene_92   7799.22 10160.219  8449.304 10615.711 10481.134 10245.078  9788.412
#> gene_93   9599.04 11527.941 10834.990  9099.181  9782.392  9039.775  7514.337
#> gene_94   8599.14  9867.136  8051.690 12738.854  9083.649  9843.311  9689.539
#> gene_95   9099.09 10746.385 10238.569  9099.181  9083.649 10747.288  8503.065
#> gene_96   8999.10 10648.691 11033.797  9806.895  8384.907  9943.753 11864.742
#> gene_97  10498.95 11918.718 10934.394  9503.589  8784.188  9341.101  9689.539
#> gene_98  11798.82 11137.163 10536.779  9402.487 10181.673  9943.753  9491.794
#> gene_99  10698.93 10648.691  9542.744  8998.079  8584.548  9943.753 10974.886
#> gene_100  9999.00 10257.913  6858.847  9705.793  8484.727  9943.753  8601.938
#>          sample_15 sample_16 sample_17 sample_18 sample_19 sample_20
#> gene_1    9576.060 10317.382  9083.649 10884.902  8793.844 10801.704
#> gene_2   11571.072 10219.122 10181.673 10683.330  8294.194 11396.294
#> gene_3   10274.314  7860.863 10181.673  9877.041  8494.054 11792.687
#> gene_4    9975.062  9629.557 11579.158  9171.538  8893.774  9711.624
#> gene_5    8079.800 10120.861 11279.697 10280.185 10892.375 10603.508
#> gene_6   12169.576 10513.904 10880.415  8566.821  8893.774 10108.017
#> gene_7   10374.065 10808.686 10880.415  9776.255 11691.816 10702.606
#> gene_8    9177.057  9727.818  9782.392  9776.255  9493.355  8324.249
#> gene_9   10773.067 10120.861 12377.720  9574.683  9193.565 10306.213
#> gene_10   8778.055 12184.337 10281.493  8969.966  9293.495  9909.821
#> gene_11   9875.312  9531.296  8983.829  9977.827 10492.655  8819.740
#> gene_12  10274.314 11201.729  9782.392  9473.896  7794.544 10504.410
#> gene_13  11870.324  9826.078  8285.087  9473.896  9793.145  8126.053
#> gene_14   9576.060 10513.904 10481.134 11086.475  9893.075  8621.544
#> gene_15   8079.800 10120.861  9482.931 11086.475  9593.285 10504.410
#> gene_16   9576.060 10808.686  9782.392 11086.475 10092.935  9909.821
#> gene_17   9675.810  9924.339 10181.673 11993.550 11092.235 11198.097
#> gene_18  11172.070 10022.600  9682.571 10481.758  9893.075 10108.017
#> gene_19   9875.312  9334.774  7785.985 10078.613 11092.235 10900.803
#> gene_20  10773.067  9727.818 11080.056 10481.758 11092.235 10603.508
#> gene_21   9775.561 10612.165 12377.720 10280.185  8693.914  9909.821
#> gene_22  10174.564  9531.296 11778.798 11086.475  9393.425  7729.660
#> gene_23  11072.319  7959.124  9982.032 10380.972 10492.655 10008.919
#> gene_24  10972.569 10710.425 10880.415  9171.538 10192.865  9315.231
#> gene_25   9476.309 11103.469  9882.212 11388.833  8394.124 11297.196
#> gene_26  11471.322 10415.643 10281.493  9877.041  9693.215  9017.937
#> gene_27   8678.304 10710.425  8584.548  7357.388  8893.774 10603.508
#> gene_28   9376.559  9433.035 10481.134  9171.538  7694.614 10900.803
#> gene_29   9975.062 10513.904  9083.649  9574.683  9393.425  8621.544
#> gene_30   9077.307 10415.643  9782.392 10683.330 10692.515  9315.231
#> gene_31  11172.070 10710.425  8884.009 11187.261  8693.914  9315.231
#> gene_32   9576.060 11987.816  9882.212  8062.891 10192.865  8819.740
#> gene_33  11072.319  9039.992 10081.853  9574.683 10092.935  9315.231
#> gene_34  10274.314 10513.904  7985.626 10683.330 10392.725 10207.115
#> gene_35  10374.065 11103.469  9083.649 10078.613 10192.865  9909.821
#> gene_36  10673.317  9433.035 11479.337  8869.180  9993.005 10504.410
#> gene_37  10274.314  9531.296  9083.649 10280.185  9993.005 10603.508
#> gene_38  10573.566  9629.557  9882.212 10683.330  9193.565  9315.231
#> gene_39  12269.327  9531.296  7586.345  9473.896 10392.725 11297.196
#> gene_40   8977.556 10219.122  8584.548 10985.688  9193.565 10999.901
#> gene_41  10473.815 11693.033  9383.110 10179.399 10492.655 10702.606
#> gene_42   9376.559  8843.471  8684.368 11288.047  9493.355  9513.428
#> gene_43   8977.556 10120.861  9183.470 11187.261  9693.215 10306.213
#> gene_44  10673.317 10710.425 10880.415  7861.318  9993.005  7927.857
#> gene_45  10872.818  9039.992  9982.032  8365.249 10092.935 10801.704
#> gene_46  10274.314  9924.339  9183.470  9776.255 11591.886 10405.312
#> gene_47  11271.820 11005.208 11479.337  8667.607 10892.375 10702.606
#> gene_48   9975.062 11693.033 10081.853  9171.538  8993.704 11098.999
#> gene_49   9476.309  9924.339 10880.415 11388.833  9293.495  9315.231
#> gene_50   8179.551  9433.035 10780.595  9373.110  9693.215 10999.901
#> gene_51   8877.805  9924.339 10580.954  9473.896 10892.375 10108.017
#> gene_52   8478.803 10120.861 10281.493 12195.122  9793.145  9216.133
#> gene_53  10274.314  8941.731  9083.649  9877.041  9393.425 10504.410
#> gene_54  10074.813 11889.555  8684.368 10078.613 11092.235 10306.213
#> gene_55   8478.803  9433.035 10780.595 10078.613 10992.305 10504.410
#> gene_56  10473.815 10906.947 11379.517  7962.104 11591.886  9315.231
#> gene_57  10274.314  8352.167  8983.829 10380.972  9693.215 10405.312
#> gene_58   9675.810 10317.382 12178.079 10380.972 11691.816  8522.446
#> gene_59   6882.793  8843.471  9982.032  9877.041  8993.704  9513.428
#> gene_60   9975.062  9629.557  9183.470 10179.399  8793.844 10504.410
#> gene_61   9975.062  9039.992  9682.571  9070.752  8893.774  8522.446
#> gene_62  11172.070  9826.078  9283.290 10481.758  9793.145  9216.133
#> gene_63  10174.564 10415.643 11579.158  9272.324 11092.235  9017.937
#> gene_64  10174.564 10022.600  9183.470 10884.902 10892.375  8423.348
#> gene_65   9376.559 11299.990 10980.236 11388.833  9093.634 10603.508
#> gene_66   9775.561  9826.078 10081.853  9373.110 10792.445 11198.097
#> gene_67  10972.569  8941.731  9383.110  8566.821 10292.795  9117.035
#> gene_68   8478.803 10808.686 10381.314  9776.255 11891.676 10999.901
#> gene_69  10573.566  9924.339 10081.853 10179.399  9793.145 10008.919
#> gene_70  11670.823  8843.471  9582.751  8969.966  9093.634 10603.508
#> gene_71  10972.569  9727.818  8983.829 10884.902 10592.585  9711.624
#> gene_72   9376.559 10120.861  8983.829 10179.399 11092.235 10306.213
#> gene_73   9975.062  9531.296 11778.798  7256.601 11392.026  8225.151
#> gene_74  10673.317  9236.514  9582.751  8566.821 12491.256  8819.740
#> gene_75   9077.307 10906.947 10081.853 10078.613  9093.634  9315.231
#> gene_76  11271.820  9236.514  9283.290  9977.827 10092.935  9612.526
#> gene_77   8279.302 10317.382  8983.829 10380.972  9293.495 10008.919
#> gene_78  10174.564 10022.600  9682.571 11489.619  9793.145 12387.276
#> gene_79   9077.307  9531.296 11279.697 10280.185  9293.495  9315.231
#> gene_80   8678.304  9924.339  9982.032  9776.255 11292.096 10008.919
#> gene_81   9476.309  9433.035 10081.853  9675.469  9893.075  9414.330
#> gene_82   9376.559  9039.992 11179.876  9675.469  9093.634  9909.821
#> gene_83   8877.805  9531.296  9383.110 10985.688 10592.585 10306.213
#> gene_84   9576.060  9629.557 10181.673  9070.752  7994.404 11198.097
#> gene_85   9975.062  9138.253 10680.775 11590.405 10092.935 11098.999
#> gene_86   9875.312 12479.120 10880.415  9675.469  9893.075  9612.526
#> gene_87  11072.319  8548.688  7686.165 10280.185 13390.627  9414.330
#> gene_88   9875.312  8548.688 11179.876 10582.544 10692.515  9810.722
#> gene_89   9875.312  7566.080  9882.212 11288.047 10492.655 11792.687
#> gene_90  10374.065 11791.294  8684.368  9776.255 10192.865 10108.017
#> gene_91   8279.302  9629.557 10780.595 10380.972  8693.914 10900.803
#> gene_92  10473.815 10808.686 11080.056 10078.613 10792.445 10801.704
#> gene_93  10074.813 10120.861  8584.548 10481.758 10292.795  8126.053
#> gene_94  10074.813  9433.035 11479.337 11288.047 10092.935  9414.330
#> gene_95  10174.564 10612.165  9283.290  8969.966 10792.445  9612.526
#> gene_96  11471.322  9433.035 10381.314  8768.393 10492.655 10900.803
#> gene_97  11271.820  9727.818  9582.751 10179.399 10792.445  9513.428
#> gene_98  10074.813 11005.208 11778.798 10582.544  8593.984 10504.410
#> gene_99   9975.062  8745.210 10181.673  9272.324 10492.655 10702.606
#> gene_100 10074.813 10906.947  8884.009 11187.261 10792.445 10801.704
#> 
#> $dge_keep
#> An object of class "DGEList"
#> $counts
#>        sample_1 sample_2 sample_3 sample_4 sample_5 sample_6 sample_7 sample_8
#> gene_1      110      107       90       99      112       85       91      109
#> gene_2      104      111       98      109      109      122      121       71
#> gene_3      102      111       90      109      118      114      101       92
#> gene_4       88       93      103       99       96       77       98       99
#> gene_5      111      105       92      103      109      104       95      110
#>        sample_9 sample_10 sample_11 sample_12 sample_13 sample_14 sample_15
#> gene_1      101       106       105       114        78        94        96
#> gene_2      108       108        93        83       125        97       116
#> gene_3      100        92       106       111        83       115       103
#> gene_4       83        94        94       108        90       105       100
#> gene_5       91       104        90        99        97       111        81
#>        sample_16 sample_17 sample_18 sample_19 sample_20
#> gene_1       105        91       108        88       109
#> gene_2       104       102       106        83       115
#> gene_3        80       102        98        85       119
#> gene_4        98       116        91        89        98
#> gene_5       103       113       102       109       107
#> 95 more rows ...
#> 
#> $samples
#>          group lib.size norm.factors
#> sample_1     1    10135    1.0031640
#> sample_2     1    10135    0.9943094
#> sample_3     1    10129    0.9965943
#> sample_4     1     9857    1.0020297
#> sample_5     1    10056    0.9970823
#> 15 more rows ...
#> 
#> 
#> $dge_keep_cpm
#>           sample_1  sample_2  sample_3  sample_4  sample_5  sample_6  sample_7
#> gene_1   10819.246 10617.896  8915.743 10023.279 11170.221  8371.044  9121.676
#> gene_2   10229.105 11014.827  9708.253 11035.732 10871.018 12014.910 12128.822
#> gene_3   10032.392 11014.827  8915.743 11035.732 11768.625 11227.047 10124.058
#> gene_4    8655.397  9228.639 10203.572 10023.279  9574.475  7583.181  9823.343
#> gene_5   10917.603 10419.431  9113.870 10428.260 10871.018 10242.219  9522.629
#> gene_6    9147.181  8633.243 11392.338  9112.072 12167.562  9454.356  9221.914
#> gene_7    9343.894  9824.035  7925.104  9415.808  9275.273 10833.116 10525.011
#> gene_8    8557.040 10816.362  9609.189  9922.034 10172.880  9848.287  9923.581
#> gene_9    8261.970  9427.104 10203.572  9213.317  9973.411 10045.253  8319.770
#> gene_10  10819.246  9030.173  9411.062 11035.732 10073.145  9060.424 10124.058
#> gene_11  10130.748  8633.243 10897.019 10428.260 10073.145  9651.321 10725.487
#> gene_12   8655.397  9724.802  8321.360  9314.563  8876.336 10340.701  9422.390
#> gene_13   9442.251  9129.406  9014.806  9618.298 10472.082  9848.287  8620.485
#> gene_14   8557.040 10518.664 10996.082  9517.053  8676.868 10439.184  9622.867
#> gene_15   8950.467  9327.871  8816.679  8200.865 10472.082  9454.356 10424.772
#> gene_16  10032.392  9824.035  8519.487  8808.336 12167.562 10045.253 12329.298
#> gene_17   9638.965  9228.639 11293.274 10731.996 10272.614  9749.804  9422.390
#> gene_18  10622.532  9327.871 12779.231  9922.034 10172.880  8961.941 10525.011
#> gene_19  12097.884  9327.871  9212.934  9415.808 10871.018 11522.496  8219.532
#> gene_20  10720.889 10022.500  9510.125  9314.563  9973.411  9257.390  9622.867
#> gene_21  11212.673  7938.614 10500.763 10124.525 10272.614 10340.701  9322.152
#> gene_22   9638.965 11114.060  8519.487 11339.468 10671.550  8666.493  8319.770
#> gene_23  11507.743 10220.966  8321.360 11643.203  9973.411  9355.873 10224.296
#> gene_24   9048.824 11213.292  8321.360  9719.544  9375.007  8568.010  9422.390
#> gene_25   8360.326 10121.733  9906.381  9517.053  9275.273  9158.907  8820.961
#> gene_26  10229.105  9824.035 10500.763 10124.525  9375.007  8961.941 10324.534
#> gene_27  11507.743  9923.268  9609.189  9213.317 10871.018  9749.804  9622.867
#> gene_28   8950.467 10220.966  9807.317 10630.751 10372.348 10340.701  8319.770
#> gene_29  10819.246 10220.966 10599.827 12554.410 11668.891  8764.975 11427.154
#> gene_30   8950.467  9923.268  9807.317  9922.034 12765.967  9749.804 10525.011
#> gene_31   9442.251 10717.129 10897.019  9314.563 10272.614 10045.253 11828.107
#> gene_32  10622.532 11411.758 11194.210  9112.072 11269.955 10734.633 10825.725
#> gene_33   8852.110  9526.337  9906.381 12048.184  9175.538  9946.770 10324.534
#> gene_34  10327.462  8335.545  9311.998  9922.034 10073.145 10537.667 10424.772
#> gene_35   9835.678 10617.896 10698.891 10934.487 10472.082  8764.975 10725.487
#> gene_36   8753.754 11213.292  9212.934 11238.222  8876.336  8764.975 11026.202
#> gene_37  10130.748 10220.966  9807.317  9517.053 10272.614  8764.975  9322.152
#> gene_38  10819.246 11510.990  9411.062 10327.015 10671.550 10734.633 10925.963
#> gene_39  12097.884  9427.104 12779.231  9820.789  9075.804  9158.907  9121.676
#> gene_40  11212.673 10617.896  9510.125 11238.222  9973.411  9158.907 10224.296
#> gene_41   9245.537  8137.079  8024.168  9922.034  9474.741  8863.458  9723.105
#> gene_42  11802.814 10419.431 11986.720  8707.091  9375.007  9454.356  9823.343
#> gene_43   7376.759 10816.362 10104.508  8605.846  9674.209  9158.907  9422.390
#> gene_44   9442.251  8633.243  9708.253  9010.827  9873.677 10734.633  9221.914
#> gene_45   9442.251  9724.802  8024.168  9314.563 10073.145  9060.424  9522.629
#> gene_46   8261.970 10121.733  8915.743 10934.487 10871.018 10045.253 10424.772
#> gene_47  11114.316  9526.337 10302.636  9415.808 10172.880 10439.184 10725.487
#> gene_48  11114.316 10518.664  9411.062 10023.279 10871.018  8469.527 10925.963
#> gene_49  10032.392 11114.060  9807.317  9719.544 12965.435  9946.770  9522.629
#> gene_50   9737.321 10022.500 10302.636 11643.203 11569.157  9848.287 10124.058
#> gene_51   9147.181  9327.871 10500.763 10225.770  9674.209  8764.975 10124.058
#> gene_52  10819.246 11312.525  9807.317 10327.015  9574.475  8666.493 11828.107
#> gene_53  10327.462 10816.362 10897.019 10934.487 10372.348 10439.184  8219.532
#> gene_54   9343.894 10518.664  9807.317 12655.656  9474.741 10734.633  8820.961
#> gene_55  10425.819  8137.079  8519.487  7998.374 10771.284  9848.287 10825.725
#> gene_56  11311.030  9923.268 10996.082  8200.865  8976.070  8272.561 10324.534
#> gene_57  10425.819 10518.664  8717.615 10225.770  9574.475 11227.047 11427.154
#> gene_58   9934.035 10022.500 10302.636  9213.317 10771.284 10734.633 10124.058
#> gene_59   9737.321 11014.827 11590.465  9415.808 10172.880  9158.907 10424.772
#> gene_60  11802.814 12999.480 10104.508 10630.751 11768.625 10636.150  9723.105
#> gene_61  10819.246 11213.292 10996.082  8504.601  9574.475 11916.427  8820.961
#> gene_62   8753.754  8831.708  8915.743 10529.506 10871.018  9946.770  9622.867
#> gene_63   9442.251 10518.664 10203.572  9213.317 10871.018 10833.116  9622.867
#> gene_64   9638.965  9030.173 10104.508 10225.770 11170.221  9060.424  8319.770
#> gene_65   9343.894 10617.896 10599.827  9618.298  8776.602  9848.287 10625.249
#> gene_66   9934.035 12205.619 12283.912 11440.713 10472.082 10143.736  8520.247
#> gene_67   9245.537  9129.406 10104.508  9213.317 10671.550 10045.253 11427.154
#> gene_68  10130.748 10220.966  9708.253 11440.713  8976.070 11227.047 10725.487
#> gene_69  11507.743 10617.896 10698.891 11136.977  8776.602  9946.770 12429.536
#> gene_70   8950.467 10022.500 10302.636 10428.260  9873.677 10143.736 10023.820
#> gene_71   9442.251 11808.688  9311.998 10023.279 10771.284 12704.290  9923.581
#> gene_72  10819.246  9724.802  9212.934  7998.374  8976.070 10340.701 11627.631
#> gene_73   9934.035  9923.268 12878.295 10023.279  9474.741 11325.530 11828.107
#> gene_74   9245.537  9923.268  9906.381 10023.279  8377.666 10143.736 10023.820
#> gene_75  10819.246 10518.664 11491.401 10630.751  8976.070 10931.599 10925.963
#> gene_76  11212.673  8930.941 10797.955 10428.260 10771.284 10242.219 10424.772
#> gene_77   9737.321  9824.035 12581.103  9112.072  9674.209 10242.219 10324.534
#> gene_78  10130.748 10816.362  9311.998 10934.487  9973.411 10636.150 10124.058
#> gene_79   9737.321  9228.639 10104.508  9922.034  8676.868  9848.287  9923.581
#> gene_80  10819.246  9923.268  9906.381  9010.827  9773.943 10833.116  8219.532
#> gene_81   8753.754  9327.871 12085.784  9719.544  9075.804  8961.941  8921.200
#> gene_82  11802.814  9526.337 10698.891  8403.355 11968.094 10537.667  9021.438
#> gene_83   9048.824  9625.570 10698.891 10124.525  9474.741  7386.215 11326.916
#> gene_84  12196.241 10022.500 10897.019 10731.996  9175.538 12014.910  9422.390
#> gene_85  10425.819  9427.104  9708.253 10023.279  8876.336 11030.081 10023.820
#> gene_86   8852.110  9129.406  9906.381 10023.279  8676.868 10242.219 12229.060
#> gene_87   8655.397  9824.035  9212.934  9820.789  9175.538 10045.253  9723.105
#> gene_88   9934.035  9327.871  9311.998 11238.222 10472.082 11030.081  9221.914
#> gene_89   9934.035  9526.337 10104.508  7998.374  8776.602  8568.010 10324.534
#> gene_90   9442.251 10518.664 11293.274  9415.808 10172.880  9848.287 10224.296
#> gene_91   9147.181 10518.664 10797.955  7390.903  7579.793 12408.842  9021.438
#> gene_92   9638.965 10617.896 10797.955 10124.525  9773.943 11817.944 10224.296
#> gene_93  10130.748 10419.431  9311.998 10731.996  9075.804 10734.633  9422.390
#> gene_94  10032.392 11213.292 10005.444  9922.034  9275.273  9552.838  9522.629
#> gene_95  10032.392 10617.896  9212.934  9517.053  9973.411  8371.044  9422.390
#> gene_96  11114.316  9824.035 10599.827  8707.091 10272.614  9848.287 11126.440
#> gene_97   9638.965  9129.406  9807.317 10124.525  8477.400  9060.424  9522.629
#> gene_98  10229.105 10915.594  9311.998  9618.298  8976.070 10045.253  8620.485
#> gene_99  10720.889  9427.104 10203.572  9618.298 10671.550 10439.184 10424.772
#> gene_100  8655.397 10717.129  8816.679 12959.391  8776.602 11916.427  9121.676
#>           sample_8  sample_9 sample_10 sample_11 sample_12 sample_13 sample_14
#> gene_1   10800.749  9919.362 10489.161 10648.227 11367.827  7826.737  9347.142
#> gene_2    7035.350 10606.843 10687.070  9431.287  8276.576 12542.848  9645.455
#> gene_3    9116.228  9821.150  9103.800 10749.639 11068.674  8328.451 11435.333
#> gene_4    9809.855  8151.555  9301.709  9532.699 10769.521  9030.851 10440.956
#> gene_5   10899.838  8937.247 10291.252  9127.052  9872.061  9733.250 11037.582
#> gene_6   10305.302 10901.477  9796.481 10141.169 10370.650 12643.191  9446.580
#> gene_7    8918.050  9133.670  8806.937  8924.229 12165.570  8930.508 10540.394
#> gene_8   11494.375  8446.189  8609.029 10039.757  8874.883 10435.650  9943.768
#> gene_9    9809.855 10115.785 10983.933 11358.109 12863.594  9331.879  9645.455
#> gene_10  10305.302  8642.612  9103.800  9938.345 11866.416  8428.794  9744.893
#> gene_11  10404.391  8839.035 10192.298 11459.521  8476.012 11740.106  8551.640
#> gene_12  10503.481 10410.420  9202.755 11256.697  9273.754  8228.108 10739.269
#> gene_13   9017.139 11588.958  9004.846 10242.580 10470.367 10535.992 10440.956
#> gene_14  10107.123  9526.516  9598.572 11053.874  9373.472 10435.650 11733.646
#> gene_15   9512.586 10901.477 11280.796  8214.347 10370.650 10034.278 10341.519
#> gene_16  10503.481 11785.381 10687.070 10039.757 10370.650 10134.621  9844.330
#> gene_17   8521.692 11294.323  9499.618  9228.464  9872.061  9833.593  9347.142
#> gene_18  10107.123 10213.996  8905.892 10141.169  8376.294  9231.536  9844.330
#> gene_19   9512.586 10606.843 11577.659 11053.874 11567.263 10636.335 11932.522
#> gene_20   8818.960 10705.054  9598.572  9836.934  8575.729 10636.335  9347.142
#> gene_21   9611.676  9428.304  9202.755 11662.344  9074.318  9131.193 10440.956
#> gene_22   8719.871  9035.458  8609.029  9127.052  9572.907  9331.879  9148.267
#> gene_23   9611.676  9133.670 11280.796 10648.227  9473.190  8328.451  8849.954
#> gene_24   8719.871  9428.304 11082.887  9532.699 10470.367  9331.879 10043.206
#> gene_25  10305.302 10115.785 10390.207 11358.109  7877.705 11238.392  9347.142
#> gene_26  10008.033 10508.631  8707.983 10648.227 10570.085 10435.650 10043.206
#> gene_27  10602.570  9133.670 10093.344  9532.699  9273.754 10134.621 10341.519
#> gene_28   9908.944  8642.612 10192.298  9735.522 10171.214  9030.851  9446.580
#> gene_29   9809.855  8053.343  9103.800 10242.580  8775.165  9933.936 10838.707
#> gene_30  10602.570  7856.920  9499.618 10141.169  9772.343 10234.964 10938.145
#> gene_31   8818.960  9821.150  9499.618  9532.699 10071.496  8930.508  8949.391
#> gene_32  10305.302 10312.208  9004.846  8822.817  9772.343 10937.364  9048.829
#> gene_33   9017.139  9821.150 10093.344  9634.110 10171.214 10435.650  9744.893
#> gene_34  10008.033  9722.939 10093.344  8619.993 12265.287  8529.137  9247.704
#> gene_35   8818.960 10999.689 10884.979 12067.991 10769.521  8529.137 10242.081
#> gene_36  10404.391  9624.727 11577.659 10952.462  9273.754 10636.335  9148.267
#> gene_37  11098.017  7660.497  9004.846  9634.110 11268.110  7726.394 12031.959
#> gene_38  10701.659 11588.958  7916.348 10952.462 10968.956 11740.106  9347.142
#> gene_39  10206.212  9624.727  9598.572 11358.109  9672.625 10837.021 11534.771
#> gene_40   9908.944 10803.266  9895.435  9431.287 10669.803 11539.420  9148.267
#> gene_41   9809.855 10410.420  8510.074 10242.580 10570.085 10234.964 10540.394
#> gene_42   9215.318  9231.881 10588.116 10546.816  9074.318 10335.307 11137.020
#> gene_43   9017.139  8839.035 10093.344 12676.461  8775.165 12041.134  7855.577
#> gene_44   9710.765 11490.746 11478.705 10242.580  9572.907 10535.992 12429.710
#> gene_45   9314.407 11588.958  9796.481 10851.051  8276.576  9833.593  8551.640
#> gene_46   9809.855 11392.535 10489.161 10445.404 10071.496 10636.335 11236.458
#> gene_47   9215.318 11294.323 10489.161 10039.757 11467.545 10034.278 10341.519
#> gene_48   9710.765  9624.727 10291.252  9735.522  9772.343 10435.650  9943.768
#> gene_49   9809.855 12178.227  9202.755  8822.817  8874.883 10335.307  8352.765
#> gene_50  11692.554  8740.824 10093.344 11560.932 10570.085 10535.992  9943.768
#> gene_51  10206.212  9919.362  8905.892 10952.462 13063.030 10736.678  7358.388
#> gene_52   8719.871  9919.362 10192.298  8112.935 10470.367  8729.822 10938.145
#> gene_53  10404.391 10999.689 10884.979  9025.640 11168.392 10636.335 10341.519
#> gene_54  10503.481 10312.208 11082.887  8315.758  9473.190 10535.992  9148.267
#> gene_55   9314.407  8937.247  9796.481 11053.874  9273.754  9532.565 10242.081
#> gene_56   8521.692 10508.631 10489.161 12676.461  8974.601 11740.106 12031.959
#> gene_57  10602.570 10803.266  9895.435 10749.639  9672.625  9632.907  9844.330
#> gene_58   9809.855 10017.573  9994.389  9228.464  9572.907  9432.222 10938.145
#> gene_59   9809.855 11687.169 11478.705 10343.992 10669.803 10134.621  9645.455
#> gene_60  11692.554 10213.996 11676.613 11560.932 10869.238  9532.565  9844.330
#> gene_61  10008.033 10508.631  8510.074  9329.875  8276.576 10034.278 10043.206
#> gene_62   9710.765  9919.362  9004.846 10952.462 10968.956  8428.794 11435.333
#> gene_63  10701.659  9821.150  9301.709 10648.227 10669.803 10134.621  9148.267
#> gene_64  10107.123  9231.881  9697.526  9025.640  8974.601 10435.650  9446.580
#> gene_65  10305.302 10115.785  8213.211  9532.699 10470.367  8228.108  9645.455
#> gene_66  10998.928  9330.093  9895.435  8112.935 11866.416 11539.420 11534.771
#> gene_67  10899.838 10017.573 12171.385  9836.934  9473.190 10837.021 10341.519
#> gene_68  11296.196  9722.939  8510.074 10648.227 11866.416 12041.134 10142.643
#> gene_69  10107.123 10017.573  9994.389  9938.345  9672.625 12342.162 10242.081
#> gene_70  10206.212  9133.670 10192.298 11358.109 10869.238  8529.137 10341.519
#> gene_71   8323.513 10312.208  9400.663 10343.992  9473.190  9532.565 10739.269
#> gene_72   9908.944 12080.015  9499.618 10141.169  9872.061  9733.250  9148.267
#> gene_73   9809.855  8937.247 10884.979  9532.699 10769.521  9532.565 11932.522
#> gene_74   8620.781  8839.035 11280.796  9836.934  9373.472 10234.964 11733.646
#> gene_75   9116.228 10901.477  8806.937 10952.462  7877.705  9331.879  9347.142
#> gene_76  11593.464 10508.631 10786.024  8619.993  9373.472  9030.851 11932.522
#> gene_77   9017.139  9133.670 10192.298 10749.639 10171.214  9933.936  9048.829
#> gene_78   9809.855  9821.150  9994.389  9634.110  9373.472  9030.851  9645.455
#> gene_79   8918.050  8937.247  9598.572  9431.287  9174.036  9733.250  9247.704
#> gene_80  10503.481 10017.573  8411.120  9938.345 10769.521  9733.250 10043.206
#> gene_81  10998.928 10312.208 10884.979 10648.227  9872.061 10535.992  8054.452
#> gene_82  10503.481 10312.208 11181.842  8721.405 10270.932 10736.678  9844.330
#> gene_83  11791.643 11687.169  9202.755  9431.287  8775.165  9231.536 10838.707
#> gene_84   9413.497 10508.631 11280.796  7808.700  9373.472 10535.992 10838.707
#> gene_85   8620.781 10410.420  9796.481  9127.052 10370.650 11539.420  9446.580
#> gene_86  10404.391  9526.516 12171.385  9329.875 10470.367 10034.278 10341.519
#> gene_87  11593.464  9722.939 10390.207  9431.287 10171.214  9131.193 10540.394
#> gene_88   8026.245  9624.727 11973.476  8822.817 10470.367  9231.536 10440.956
#> gene_89  11197.107 10017.573 11082.887 10445.404 11367.827  9733.250 11137.020
#> gene_90  10998.928  9526.516  9400.663  8924.229 11367.827 10134.621 11137.020
#> gene_91  11593.464  8937.247  9796.481  9329.875  9971.778  9632.907  9446.580
#> gene_92   7728.976 10213.996  8411.120 10648.227 10470.367 10234.964  9844.330
#> gene_93   9512.586 11588.958 10786.024  9127.052  9772.343  9030.851  7557.264
#> gene_94   8521.692  9919.362  8015.302 12777.873  9074.318  9833.593  9744.893
#> gene_95   9017.139 10803.266 10192.298  9127.052  9074.318 10736.678  8551.640
#> gene_96   8918.050 10705.054 10983.933  9836.934  8376.294  9933.936 11932.522
#> gene_97  10404.391 11981.804 10884.979  9532.699  8775.165  9331.879  9744.893
#> gene_98  11692.554 11196.112 10489.161  9431.287 10171.214  9933.936  9546.017
#> gene_99  10602.570 10705.054  9499.618  9025.640  8575.729  9933.936 11037.582
#> gene_100  9908.944 10312.208  6827.850  9735.522  8476.012  9933.936  8651.078
#>          sample_15 sample_16 sample_17 sample_18 sample_19 sample_20
#> gene_1    9565.422 10320.630  9098.526 10809.819  8804.398 10825.202
#> gene_2   11558.218 10222.338 10198.348 10609.637  8304.148 11421.084
#> gene_3   10262.901  7863.337 10198.348  9808.910  8504.248 11818.339
#> gene_4    9963.981  9632.588 11598.121  9108.274  8904.448  9732.750
#> gene_5    8070.825 10124.047 11298.170 10209.274 10905.447 10626.574
#> gene_6   12156.057 10517.214 10898.235  8507.728  8904.448 10130.005
#> gene_7   10362.541 10812.089 10898.235  9708.819 11705.847 10725.888
#> gene_8    9166.863  9730.880  9798.413  9708.819  9504.748  8342.357
#> gene_9   10761.100 10124.047 12397.992  9508.637  9204.598 10328.633
#> gene_10   8768.304 12188.173 10298.332  8908.092  9304.648  9931.378
#> gene_11   9864.342  9534.296  8998.542  9909.001 10505.247  8838.926
#> gene_12  10262.901 11205.256  9798.413  9408.546  7803.898 10527.260
#> gene_13  11857.138  9829.172  8298.656  9408.546  9804.897  8143.730
#> gene_14   9565.422 10517.214 10498.299 11010.001  9904.947  8640.299
#> gene_15   8070.825 10124.047  9498.461 11010.001  9604.798 10527.260
#> gene_16   9565.422 10812.089  9798.413 11010.001 10105.047  9931.378
#> gene_17   9665.062  9927.463 10198.348 11910.819 11105.547 11222.457
#> gene_18  11159.659 10025.755  9698.429 10409.456  9904.947 10130.005
#> gene_19   9864.342  9337.713  7798.737 10009.092 11105.547 10924.515
#> gene_20  10761.100  9730.880 11098.202 10409.456 11105.547 10626.574
#> gene_21   9764.702 10615.505 12397.992 10209.274  8704.348  9931.378
#> gene_22  10163.261  9534.296 11798.089 11010.001  9404.698  7746.475
#> gene_23  11060.019  7961.629  9998.380 10309.365 10505.247 10030.691
#> gene_24  10960.379 10713.797 10898.235  9108.274 10205.097  9335.495
#> gene_25   9465.782 11106.964  9898.396 11310.274  8404.198 11321.771
#> gene_26  11458.579 10418.922 10298.332  9808.910  9704.848  9037.554
#> gene_27   8668.664 10713.797  8598.607  7306.637  8904.448 10626.574
#> gene_28   9366.142  9436.005 10498.299  9108.274  7703.848 10924.515
#> gene_29   9963.981 10517.214  9098.526  9508.637  9404.698  8640.299
#> gene_30   9067.223 10418.922  9798.413 10609.637 10705.347  9335.495
#> gene_31  11159.659 10713.797  8898.558 11110.092  8704.348  9335.495
#> gene_32   9565.422 11991.589  9898.396  8007.273 10205.097  8838.926
#> gene_33  11060.019  9042.838 10098.364  9508.637 10105.047  9335.495
#> gene_34  10262.901 10517.214  7998.704 10609.637 10405.197 10229.319
#> gene_35  10362.541 11106.964  9098.526 10009.092 10205.097  9931.378
#> gene_36  10661.460  9436.005 11498.137  8808.001 10004.997 10527.260
#> gene_37  10262.901  9534.296  9098.526 10209.274 10004.997 10626.574
#> gene_38  10561.820  9632.588  9898.396 10609.637  9204.598  9335.495
#> gene_39  12255.697  9534.296  7598.769  9408.546 10405.197 11321.771
#> gene_40   8967.583 10222.338  8598.607 10909.910  9204.598 11023.829
#> gene_41  10462.180 11696.714  9398.477 10109.183 10505.247 10725.888
#> gene_42   9366.142  8846.254  8698.591 11210.183  9504.748  9534.123
#> gene_43   8967.583 10124.047  9198.510 11110.092  9704.848 10328.633
#> gene_44  10661.460 10713.797 10898.235  7807.092 10004.997  7945.102
#> gene_45  10860.740  9042.838  9998.380  8307.546 10105.047 10825.202
#> gene_46  10262.901  9927.463  9198.510  9708.819 11605.797 10427.947
#> gene_47  11259.299 11008.672 11498.137  8607.819 10905.447 10725.888
#> gene_48   9963.981 11696.714 10098.364  9108.274  9004.498 11123.143
#> gene_49   9465.782  9927.463 10898.235 11310.274  9304.648  9335.495
#> gene_50   8170.465  9436.005 10798.251  9308.455  9704.848 11023.829
#> gene_51   8867.943  9927.463 10598.283  9408.546 10905.447 10130.005
#> gene_52   8469.384 10124.047 10298.332 12111.001  9804.897  9236.181
#> gene_53  10262.901  8944.546  9098.526  9808.910  9404.698 10527.260
#> gene_54  10063.621 11893.298  8698.591 10009.092 11105.547 10328.633
#> gene_55   8469.384  9436.005 10798.251 10009.092 11005.497 10527.260
#> gene_56  10462.180 10910.380 11398.154  7907.183 11605.797  9335.495
#> gene_57  10262.901  8354.796  8998.542 10309.365  9704.848 10427.947
#> gene_58   9665.062 10320.630 12198.024 10309.365 11705.847  8540.985
#> gene_59   6875.147  8846.254  9998.380  9808.910  9004.498  9534.123
#> gene_60   9963.981  9632.588  9198.510 10109.183  8804.398 10527.260
#> gene_61   9963.981  9042.838  9698.429  9008.183  8904.448  8540.985
#> gene_62  11159.659  9829.172  9298.494 10409.456  9804.897  9236.181
#> gene_63  10163.261 10418.922 11598.121  9208.364 11105.547  9037.554
#> gene_64  10163.261 10025.755  9198.510 10809.819 10905.447  8441.671
#> gene_65   9366.142 11303.547 10998.218 11310.274  9104.548 10626.574
#> gene_66   9764.702  9829.172 10098.364  9308.455 10805.397 11222.457
#> gene_67  10960.379  8944.546  9398.477  8507.728 10305.147  9136.867
#> gene_68   8469.384 10812.089 10398.316  9708.819 11905.947 11023.829
#> gene_69  10561.820  9927.463 10098.364 10109.183  9804.897 10030.691
#> gene_70  11657.858  8846.254  9598.445  8908.092  9104.548 10626.574
#> gene_71  10960.379  9730.880  8998.542 10809.819 10605.297  9732.750
#> gene_72   9366.142 10124.047  8998.542 10109.183 11105.547 10328.633
#> gene_73   9963.981  9534.296 11798.089  7206.546 11405.697  8243.043
#> gene_74  10661.460  9239.421  9598.445  8507.728 12506.247  8838.926
#> gene_75   9067.223 10910.380 10098.364 10009.092  9104.548  9335.495
#> gene_76  11259.299  9239.421  9298.494  9909.001 10105.047  9633.436
#> gene_77   8270.105 10320.630  8998.542 10309.365  9304.648 10030.691
#> gene_78  10163.261 10025.755  9698.429 11410.365  9804.897 12414.222
#> gene_79   9067.223  9534.296 11298.170 10209.274  9304.648  9335.495
#> gene_80   8668.664  9927.463  9998.380  9708.819 11305.647 10030.691
#> gene_81   9465.782  9436.005 10098.364  9608.728  9904.947  9434.809
#> gene_82   9366.142  9042.838 11198.186  9608.728  9104.548  9931.378
#> gene_83   8867.943  9534.296  9398.477 10909.910 10605.297 10328.633
#> gene_84   9565.422  9632.588 10198.348  9008.183  8003.998 11222.457
#> gene_85   9963.981  9141.129 10698.267 11510.456 10105.047 11123.143
#> gene_86   9864.342 12483.048 10898.235  9608.728  9904.947  9633.436
#> gene_87  11060.019  8551.379  7698.753 10209.274 13406.697  9434.809
#> gene_88   9864.342  8551.379 11198.186 10509.546 10705.347  9832.064
#> gene_89   9864.342  7568.462  9898.396 11210.183 10505.247 11818.339
#> gene_90  10362.541 11795.006  8698.591  9708.819 10205.097 10130.005
#> gene_91   8270.105  9632.588 10798.251 10309.365  8704.348 10924.515
#> gene_92  10462.180 10812.089 11098.202 10009.092 10805.397 10825.202
#> gene_93  10063.621 10124.047  8598.607 10409.456 10305.147  8143.730
#> gene_94  10063.621  9436.005 11498.137 11210.183 10105.047  9434.809
#> gene_95  10163.261 10615.505  9298.494  8908.092 10805.397  9633.436
#> gene_96  11458.579  9436.005 10398.316  8707.910 10505.247 10924.515
#> gene_97  11259.299  9730.880  9598.445 10109.183 10805.397  9534.123
#> gene_98  10063.621 11008.672 11798.089 10509.546  8604.298 10527.260
#> gene_99   9963.981  8747.963 10198.348  9208.364 10505.247 10725.888
#> gene_100 10063.621 10910.380  8898.558 11110.092 10805.397 10825.202
#> 
#> $dge_keep_cpm_log
#>          sample_1 sample_2 sample_3 sample_4 sample_5 sample_6 sample_7
#> gene_1   13.40145 13.37435 13.12230 13.29121 13.44750 13.03136 13.15524
#> gene_2   13.32053 13.42729 13.24514 13.43003 13.40833 13.55266 13.56627
#> gene_3   13.29252 13.42729 13.12230 13.43003 13.52278 13.45482 13.30564
#> gene_4   13.07955 13.17206 13.31693 13.29121 13.22513 12.88878 13.26215
#> gene_5   13.41450 13.34713 13.15401 13.34835 13.40833 13.32238 13.21730
#> gene_6   13.15927 13.07585 13.47590 13.15372 13.57087 13.20692 13.17101
#> gene_7   13.18996 13.26225 12.95240 13.20102 13.17933 13.40329 13.36167
#> gene_8   13.06306 13.40106 13.23035 13.27657 13.31258 13.26580 13.27679
#> gene_9   13.01244 13.20275 13.31693 13.16966 13.28402 13.29437 13.02250
#> gene_10  13.40145 13.14070 13.20030 13.43003 13.29837 13.14552 13.30564
#> gene_11  13.30660 13.07585 13.41178 13.34835 13.29837 13.23666 13.38889
#> gene_12  13.07955 13.24760 13.02278 13.18543 13.11591 13.33619 13.20203
#> gene_13  13.20507 13.15646 13.13824 13.23172 13.35440 13.26580 13.07372
#> gene_14  13.06306 13.36080 13.42483 13.21645 13.08312 13.34986 13.23240
#> gene_15  13.12791 13.18749 13.10618 13.00174 13.35440 13.20692 13.34787
#> gene_16  13.29252 13.26225 13.05672 13.10482 13.57087 13.29437 13.58992
#> gene_17  13.23481 13.17206 13.46330 13.38977 13.32666 13.25131 13.20203
#> gene_18  13.37498 13.18749 13.64163 13.27657 13.31258 13.12976 13.36167
#> gene_19  13.56259 13.18749 13.16960 13.20102 13.40833 13.49229 13.00502
#> gene_20  13.38827 13.29110 13.21540 13.18543 13.28402 13.17655 13.23240
#> gene_21  13.45297 12.95485 13.35834 13.30571 13.32666 13.33619 13.18660
#> gene_22  13.23481 13.44023 13.05672 13.46919 13.38162 13.08140 13.02250
#> gene_23  13.49044 13.31939 13.02278 13.50732 13.28402 13.19181 13.31985
#> gene_24  13.14367 13.45305 13.02278 13.24682 13.19476 13.06491 13.20203
#> gene_25  13.02952 13.30531 13.27429 13.21645 13.17933 13.16112 13.10688
#> gene_26  13.32053 13.26225 13.35834 13.30571 13.19476 13.12976 13.33393
#> gene_27  13.49044 13.27674 13.23035 13.16966 13.40833 13.25131 13.23240
#> gene_28  13.12791 13.31939 13.25979 13.37609 13.34059 13.33619 13.02250
#> gene_29  13.40145 13.31939 13.37189 13.61602 13.51050 13.09770 13.48030
#> gene_30  13.12791 13.27674 13.25979 13.27657 13.64013 13.25131 13.36167
#> gene_31  13.20507 13.38777 13.41178 13.18543 13.32666 13.29437 13.53005
#> gene_32  13.37498 13.47836 13.45059 13.15372 13.46032 13.39012 13.40231
#> gene_33  13.11197 13.21786 13.27429 13.55665 13.16373 13.28016 13.33393
#> gene_34  13.33434 13.02523 13.18503 13.27657 13.29837 13.36340 13.34787
#> gene_35  13.26396 13.37435 13.38531 13.41673 13.35440 13.09770 13.38889
#> gene_36  13.09585 13.45305 13.16960 13.45625 13.11591 13.09770 13.42878
#> gene_37  13.30660 13.31939 13.25979 13.21645 13.32666 13.09770 13.18660
#> gene_38  13.40145 13.49085 13.20030 13.33428 13.38162 13.39012 13.41560
#> gene_39  13.56259 13.20275 13.64163 13.26177 13.14797 13.16112 13.15524
#> gene_40  13.45297 13.37435 13.21540 13.45625 13.28402 13.16112 13.31985
#> gene_41  13.17470 12.99047 12.97032 13.27657 13.21002 13.11382 13.24735
#> gene_42  13.52697 13.34713 13.54927 13.08814 13.19476 13.20692 13.26215
#> gene_43  12.84897 13.40106 13.30285 13.07127 13.24008 13.16112 13.20203
#> gene_44  13.20507 13.07585 13.24514 13.13760 13.26952 13.39012 13.17101
#> gene_45  13.20507 13.24760 12.97032 13.18543 13.29837 13.14552 13.21730
#> gene_46  13.01244 13.30531 13.12230 13.41673 13.40833 13.29437 13.34787
#> gene_47  13.44026 13.21786 13.33087 13.20102 13.31258 13.34986 13.38889
#> gene_48  13.44026 13.36080 13.20030 13.29121 13.40833 13.04824 13.41560
#> gene_49  13.29252 13.44023 13.25979 13.24682 13.66249 13.28016 13.21730
#> gene_50  13.24946 13.29110 13.33087 13.50732 13.49812 13.26580 13.30564
#> gene_51  13.15927 13.18749 13.35834 13.32006 13.24008 13.09770 13.30564
#> gene_52  13.40145 13.46576 13.25979 13.33428 13.22513 13.08140 13.53005
#> gene_53  13.33434 13.40106 13.41178 13.41673 13.34059 13.34986 13.00502
#> gene_54  13.18996 13.36080 13.25979 13.62761 13.21002 13.39012 13.10688
#> gene_55  13.34801 12.99047 13.05672 12.96567 13.39504 13.26580 13.40231
#> gene_56  13.46557 13.27674 13.42483 13.00174 13.13203 13.01429 13.33393
#> gene_57  13.34801 13.36080 13.08988 13.32006 13.22513 13.45482 13.48030
#> gene_58  13.27831 13.29110 13.33087 13.16966 13.39504 13.39012 13.30564
#> gene_59  13.24946 13.42729 13.50078 13.20102 13.31258 13.16112 13.34787
#> gene_60  13.52697 13.66628 13.30285 13.37609 13.52278 13.37682 13.24735
#> gene_61  13.40145 13.45305 13.42483 13.05420 13.22513 13.54079 13.10688
#> gene_62  13.09585 13.10864 13.12230 13.36229 13.40833 13.28016 13.23240
#> gene_63  13.20507 13.36080 13.31693 13.16966 13.40833 13.40329 13.23240
#> gene_64  13.23481 13.14070 13.30285 13.32006 13.44750 13.14552 13.02250
#> gene_65  13.18996 13.37435 13.37189 13.23172 13.09961 13.26580 13.37534
#> gene_66  13.27831 13.57538 13.58460 13.48202 13.35440 13.30844 13.05685
#> gene_67  13.17470 13.15646 13.30285 13.16966 13.38162 13.29437 13.48030
#> gene_68  13.30660 13.31939 13.24514 13.48202 13.13203 13.45482 13.38889
#> gene_69  13.49044 13.37435 13.38531 13.44320 13.09961 13.28016 13.60160
#> gene_70  13.12791 13.29110 13.33087 13.34835 13.26952 13.30844 13.29129
#> gene_71  13.20507 13.52768 13.18503 13.29121 13.39504 13.63314 13.27679
#> gene_72  13.40145 13.24760 13.16960 12.96567 13.13203 13.33619 13.50539
#> gene_73  13.27831 13.27674 13.65277 13.29121 13.21002 13.46742 13.53005
#> gene_74  13.17470 13.27674 13.27429 13.29121 13.03250 13.30844 13.29129
#> gene_75  13.40145 13.36080 13.48839 13.37609 13.13203 13.41635 13.41560
#> gene_76  13.45297 13.12476 13.39860 13.34835 13.39504 13.32238 13.34787
#> gene_77  13.24946 13.26225 13.61909 13.15372 13.24008 13.32238 13.33393
#> gene_78  13.30660 13.40106 13.18503 13.41673 13.28402 13.37682 13.30564
#> gene_79  13.24946 13.17206 13.30285 13.27657 13.08312 13.26580 13.27679
#> gene_80  13.40145 13.27674 13.27429 13.13760 13.25487 13.40329 13.00502
#> gene_81  13.09585 13.18749 13.56114 13.24682 13.14797 13.12976 13.12318
#> gene_82  13.52697 13.21786 13.38531 13.03692 13.54703 13.36340 13.13930
#> gene_83  13.14367 13.23281 13.38531 13.30571 13.21002 12.85081 13.46759
#> gene_84  13.57427 13.29110 13.41178 13.38977 13.16373 13.55266 13.20203
#> gene_85  13.34801 13.20275 13.24514 13.29121 13.11591 13.42929 13.29129
#> gene_86  13.11197 13.15646 13.27429 13.29121 13.08312 13.32238 13.57814
#> gene_87  13.07955 13.26225 13.16960 13.26177 13.16373 13.29437 13.24735
#> gene_88  13.27831 13.18749 13.18503 13.45625 13.35440 13.42929 13.17101
#> gene_89  13.27831 13.21786 13.30285 12.96567 13.09961 13.06491 13.33393
#> gene_90  13.20507 13.36080 13.46330 13.20102 13.31258 13.26580 13.31985
#> gene_91  13.15927 13.36080 13.39860 12.85173 12.88813 13.59920 13.13930
#> gene_92  13.23481 13.37435 13.39860 13.30571 13.25487 13.52881 13.31985
#> gene_93  13.30660 13.34713 13.18503 13.38977 13.14797 13.39012 13.20203
#> gene_94  13.29252 13.45305 13.28864 13.27657 13.17933 13.22186 13.21730
#> gene_95  13.29252 13.37435 13.16960 13.21645 13.28402 13.03136 13.20203
#> gene_96  13.44026 13.26225 13.37189 13.08814 13.32666 13.26580 13.44183
#> gene_97  13.23481 13.15646 13.25979 13.30571 13.04958 13.14552 13.21730
#> gene_98  13.32053 13.41424 13.18503 13.23172 13.13203 13.29437 13.07372
#> gene_99  13.38827 13.20275 13.31693 13.23172 13.38162 13.34986 13.34787
#> gene_100 13.07955 13.38777 13.10618 13.66182 13.09961 13.54079 13.15524
#>          sample_8 sample_9 sample_10 sample_11 sample_12 sample_13 sample_14
#> gene_1   13.39898 13.27618  13.35675  13.37846  13.47280  12.93438  13.19046
#> gene_2   12.78061 13.37284  13.38371  13.20339  13.01499  13.61469  13.23578
#> gene_3   13.15438 13.26182  13.15241  13.39213  13.43433  13.02401  13.48134
#> gene_4   13.26016 12.99304  13.18344  13.21882  13.39480  13.14081  13.35010
#> gene_5   13.41215 13.12578  13.32927  13.15609  13.26928  13.24885  13.43027
#> gene_6   13.33124 13.41237  13.25820  13.30808  13.34036  13.62619  13.20573
#> gene_7   13.12267 13.15714  13.10459  13.12367  13.57063  13.12469  13.36378
#> gene_8   13.48877 13.04426  13.07180  13.29358  13.11567  13.34937  13.27972
#> gene_9   13.26016 13.30446  13.42324  13.47156  13.65112  13.18811  13.23578
#> gene_10  13.33124 13.07742  13.15241  13.27894  13.53472  13.04128  13.25058
#> gene_11  13.34504 13.10984  13.31533  13.48438  13.04934  13.51928  13.06215
#> gene_12  13.35872 13.34588  13.16801  13.45862  13.17909  13.00652  13.39074
#> gene_13  13.13861 13.50059  13.13665  13.32243  13.35416  13.36318  13.35010
#> gene_14  13.30323 13.21788  13.22875  13.43239  13.19452  13.34937  13.51849
#> gene_15  13.21577 13.41237  13.46171  13.00411  13.34036  13.29279  13.33630
#> gene_16  13.35872 13.52483  13.38371  13.29358  13.34036  13.30715  13.26522
#> gene_17  13.05709 13.46344  13.21381  13.17203  13.26928  13.26365  13.19046
#> gene_18  13.30323 13.31840  13.12071  13.30808  13.03227  13.17251  13.26522
#> gene_19  13.21577 13.37284  13.49918  13.43239  13.49788  13.37685  13.54273
#> gene_20  13.10656 13.38614  13.22875  13.26414  13.06621  13.37685  13.19046
#> gene_21  13.23072 13.20294  13.16801  13.50969  13.14773  13.15675  13.35010
#> gene_22  13.09026 13.14154  13.07180  13.15609  13.22489  13.18811  13.15944
#> gene_23  13.23072 13.15714  13.46171  13.37846  13.20979  13.02401  13.11162
#> gene_24  13.09026 13.20294  13.43618  13.21882  13.35416  13.18811  13.29408
#> gene_25  13.33124 13.30446  13.34308  13.47156  12.94374  13.45628  13.19046
#> gene_26  13.28902 13.35942  13.08829  13.37846  13.36784  13.34937  13.29408
#> gene_27  13.37226 13.15714  13.30126  13.21882  13.17909  13.30715  13.33630
#> gene_28  13.27466 13.07742  13.31533  13.24919  13.31235  13.14081  13.20573
#> gene_29  13.26016 12.97555  13.15241  13.32243  13.09937  13.27829  13.40404
#> gene_30  13.37226 12.93993  13.21381  13.30808  13.25464  13.32136  13.41721
#> gene_31  13.10656 13.26182  13.21381  13.21882  13.29813  13.12469  13.12774
#> gene_32  13.33124 13.33221  13.13665  13.10719  13.25464  13.41711  13.14367
#> gene_33  13.13861 13.26182  13.30126  13.23409  13.31235  13.34937  13.25058
#> gene_34  13.28902 13.24733  13.30126  13.07364  13.58241  13.05835  13.17504
#> gene_35  13.10656 13.42531  13.41018  13.55902  13.39480  13.05835  13.32236
#> gene_36  13.34504 13.23268  13.49918  13.41910  13.17909  13.37685  13.15944
#> gene_37  13.43814 12.90341  13.13665  13.23409  13.46009  12.91577  13.55470
#> gene_38  13.38568 13.50059  12.95080  13.41910  13.42127  13.51928  13.19046
#> gene_39  13.31730 13.23268  13.22875  13.47156  13.23984  13.40381  13.49383
#> gene_40  13.27466 13.39931  13.27269  13.20339  13.38138  13.49441  13.15944
#> gene_41  13.26016 13.34588  13.05513  13.32243  13.36784  13.32136  13.36378
#> gene_42  13.16997 13.17257  13.37029  13.36466  13.14773  13.33543  13.44321
#> gene_43  13.13861 13.10984  13.30126  13.62998  13.09937  13.55580  12.93969
#> gene_44  13.24552 13.48831  13.48680  13.32243  13.22489  13.36318  13.60162
#> gene_45  13.18540 13.50059  13.25820  13.40568  13.01499  13.26365  13.06215
#> gene_46  13.26016 13.47593  13.35675  13.35072  13.29813  13.37685  13.45603
#> gene_47  13.16997 13.46344  13.35675  13.29358  13.48539  13.29279  13.33630
#> gene_48  13.24552 13.23268  13.32927  13.24919  13.25464  13.34937  13.27972
#> gene_49  13.26016 13.57213  13.16801  13.10719  13.11567  13.33543  13.02821
#> gene_50  13.51343 13.09372  13.30126  13.49709  13.36784  13.36318  13.27972
#> gene_51  13.31730 13.27618  13.12071  13.41910  13.67331  13.39039  12.84537
#> gene_52  13.09026 13.27618  13.31533  12.98619  13.35416  13.09190  13.41721
#> gene_53  13.34504 13.42531  13.41018  13.13997  13.44726  13.37685  13.33630
#> gene_54  13.35872 13.33221  13.43618  13.02181  13.20979  13.36318  13.15944
#> gene_55  13.18540 13.12578  13.25820  13.43239  13.17909  13.21880  13.32236
#> gene_56  13.05709 13.35942  13.35675  13.62998  13.13179  13.51928  13.55470
#> gene_57  13.37226 13.39931  13.27269  13.39213  13.23984  13.23391  13.26522
#> gene_58  13.26016 13.29039  13.28705  13.17203  13.22489  13.20353  13.41721
#> gene_59  13.26016 13.51276  13.48680  13.33664  13.38138  13.30715  13.23578
#> gene_60  13.51343 13.31840  13.51146  13.49709  13.40810  13.21880  13.26522
#> gene_61  13.28902 13.35942  13.05513  13.18780  13.01499  13.29279  13.29408
#> gene_62  13.24552 13.27618  13.13665  13.41910  13.42127  13.04128  13.48134
#> gene_63  13.38568 13.26182  13.18344  13.37846  13.38138  13.30715  13.15944
#> gene_64  13.30323 13.17257  13.24355  13.13997  13.13179  13.34937  13.20573
#> gene_65  13.33124 13.30446  13.00391  13.21882  13.35416  13.00652  13.23578
#> gene_66  13.42521 13.18783  13.27269  12.98619  13.53472  13.49441  13.49383
#> gene_67  13.41215 13.29039  13.57132  13.26414  13.20979  13.40381  13.33630
#> gene_68  13.46368 13.24733  13.05513  13.37846  13.53472  13.55580  13.30829
#> gene_69  13.30323 13.29039  13.28705  13.27894  13.23984  13.59142  13.32236
#> gene_70  13.31730 13.15714  13.31533  13.47156  13.40810  13.05835  13.33630
#> gene_71  13.02315 13.33221  13.19870  13.33664  13.20979  13.21880  13.39074
#> gene_72  13.27466 13.56045  13.21381  13.30808  13.26928  13.24885  13.15944
#> gene_73  13.26016 13.12578  13.41018  13.21882  13.39480  13.21880  13.54273
#> gene_74  13.07377 13.10984  13.46171  13.26414  13.19452  13.32136  13.51849
#> gene_75  13.15438 13.41237  13.10459  13.41910  12.94374  13.18811  13.19046
#> gene_76  13.50115 13.35942  13.39701  13.07364  13.19452  13.14081  13.54273
#> gene_77  13.13861 13.15714  13.31533  13.39213  13.31235  13.27829  13.14367
#> gene_78  13.26016 13.26182  13.28705  13.23409  13.19452  13.14081  13.23578
#> gene_79  13.12267 13.12578  13.22875  13.20339  13.16350  13.24885  13.17504
#> gene_80  13.35872 13.29039  13.03825  13.27894  13.39480  13.24885  13.29408
#> gene_81  13.42521 13.33221  13.41018  13.37846  13.26928  13.36318  12.97575
#> gene_82  13.35872 13.33221  13.44900  13.09051  13.32642  13.39039  13.26522
#> gene_83  13.52560 13.51276  13.16801  13.20339  13.09937  13.17251  13.40404
#> gene_84  13.20067 13.35942  13.46171  12.93105  13.19452  13.36318  13.40404
#> gene_85  13.07377 13.34588  13.25820  13.15609  13.34036  13.49441  13.20573
#> gene_86  13.34504 13.21788  13.57132  13.18780  13.35416  13.29279  13.33630
#> gene_87  13.50115 13.24733  13.34308  13.20339  13.31235  13.15675  13.36378
#> gene_88  12.97069 13.23268  13.54767  13.10719  13.35416  13.17251  13.35010
#> gene_89  13.45097 13.29039  13.43618  13.35072  13.47280  13.24885  13.44321
#> gene_90  13.42521 13.21788  13.19870  13.12367  13.47280  13.30715  13.44321
#> gene_91  13.50115 13.12578  13.25820  13.18780  13.28378  13.23391  13.20573
#> gene_92  12.91625 13.31840  13.03825  13.37846  13.35416  13.32136  13.26522
#> gene_93  13.21577 13.50059  13.39701  13.15609  13.25464  13.14081  12.88384
#> gene_94  13.05709 13.27618  12.96872  13.64147  13.14773  13.26365  13.25058
#> gene_95  13.13861 13.39931  13.31533  13.15609  13.14773  13.39039  13.06215
#> gene_96  13.12267 13.38614  13.42324  13.26414  13.03227  13.27829  13.54273
#> gene_97  13.34504 13.54868  13.41018  13.21882  13.09937  13.18811  13.25058
#> gene_98  13.51343 13.45084  13.35675  13.20339  13.31235  13.27829  13.22083
#> gene_99  13.37226 13.38614  13.21381  13.13997  13.06621  13.27829  13.43027
#> gene_100 13.27466 13.33221  12.73743  13.24919  13.04934  13.27829  13.07883
#>          sample_15 sample_16 sample_17 sample_18 sample_19 sample_20
#> gene_1    13.22376  13.33338  13.15158  13.40019  13.10417  13.40224
#> gene_2    13.49676  13.31958  13.31619  13.37322  13.01979  13.47954
#> gene_3    13.32529  12.94111  13.31619  13.26002  13.05414  13.52886
#> gene_4    13.28265  13.23386  13.50173  13.15312  13.12047  13.24878
#> gene_5    12.97868  13.30564  13.46393  13.31773  13.41289  13.37552
#> gene_6    13.56951  13.36060  13.41194  13.05473  13.12047  13.30649
#> gene_7    13.33923  13.40049  13.41194  13.24523  13.51506  13.38894
#> gene_8    13.16237  13.24850  13.25848  13.24523  13.21458  13.02641
#> gene_9    13.39367  13.30564  13.59794  13.21517  13.16830  13.33450
#> gene_10   13.09825  13.57331  13.33026  13.12106  13.18389  13.27792
#> gene_11   13.26815  13.21906  13.13564  13.27467  13.35896  13.10982
#> gene_12   13.32529  13.45202  13.25848  13.19991  12.93016  13.36198
#> gene_13   13.53359  13.26300  13.01884  13.19991  13.25943  12.99165
#> gene_14   13.22376  13.36060  13.35801  13.42666  13.27408  13.07703
#> gene_15   12.97868  13.30564  13.21363  13.42666  13.22969  13.36198
#> gene_16   13.22376  13.40049  13.25848  13.42666  13.30293  13.27792
#> gene_17   13.23871  13.27735  13.31619  13.54011  13.43912  13.45423
#> gene_18   13.44613  13.29157  13.24368  13.34575  13.27408  13.30649
#> gene_19   13.26815  13.18901  12.92921  13.28917  13.43912  13.41541
#> gene_20   13.39367  13.24850  13.43817  13.34575  13.43912  13.37552
#> gene_21   13.25351  13.37402  13.59794  13.31773  13.08769  13.27792
#> gene_22   13.31122  13.21906  13.52639  13.42666  13.19932  12.91951
#> gene_23   13.43320  12.95903  13.28762  13.33181  13.35896  13.29228
#> gene_24   13.42014  13.38732  13.41194  13.15312  13.31714  13.18867
#> gene_25   13.20866  13.43931  13.27312  13.46547  13.03707  13.46694
#> gene_26   13.48427  13.34706  13.33026  13.26002  13.24464  13.14188
#> gene_27   13.08176  13.38732  13.07006  12.83519  13.12047  13.37552
#> gene_28   13.19339  13.20411  13.35801  13.15312  12.91155  13.41541
#> gene_29   13.28265  13.36060  13.15158  13.21517  13.19932  13.07703
#> gene_30   13.14660  13.34706  13.25848  13.37322  13.38618  13.18867
#> gene_31   13.44613  13.38732  13.11952  13.43971  13.08769  13.18867
#> gene_32   13.22376  13.54986  13.27312  12.96728  13.31714  13.10982
#> gene_33   13.43320  13.14272  13.30198  13.21517  13.30293  13.18867
#> gene_34   13.32529  13.36060  12.96573  13.37322  13.34516  13.32056
#> gene_35   13.33923  13.43931  13.15158  13.28917  13.31714  13.27792
#> gene_36   13.38025  13.20411  13.48924  13.10476  13.28858  13.36198
#> gene_37   13.32529  13.21906  13.15158  13.31773  13.28858  13.37552
#> gene_38   13.36671  13.23386  13.27312  13.37322  13.16830  13.18867
#> gene_39   13.58128  13.21906  12.89174  13.19991  13.34516  13.46694
#> gene_40   13.13066  13.31958  13.07006  13.41348  13.16830  13.42847
#> gene_41   13.35303  13.51394  13.19836  13.30352  13.35896  13.38894
#> gene_42   13.19339  13.11101  13.08673  13.45265  13.21458  13.21904
#> gene_43   13.13066  13.30564  13.16734  13.43971  13.24464  13.33450
#> gene_44   13.38025  13.38732  13.41194  12.93075  13.28858  12.95603
#> gene_45   13.40697  13.14272  13.28762  13.02038  13.30293  13.40224
#> gene_46   13.32529  13.27735  13.16734  13.24523  13.50268  13.34831
#> gene_47   13.45896  13.42648  13.48924  13.07160  13.41289  13.38894
#> gene_48   13.28265  13.51394  13.30198  13.15312  13.13659  13.44141
#> gene_49   13.20866  13.27735  13.41194  13.46547  13.18389  13.18867
#> gene_50   12.99638  13.20411  13.39864  13.18448  13.24464  13.42847
#> gene_51   13.11455  13.27735  13.37168  13.19991  13.41289  13.30649
#> gene_52   13.04821  13.30564  13.33026  13.56415  13.25943  13.17324
#> gene_53   13.32529  13.12695  13.15158  13.26002  13.19932  13.36198
#> gene_54   13.29701  13.53798  13.08673  13.28917  13.43912  13.33450
#> gene_55   13.04821  13.20411  13.39864  13.28917  13.42607  13.36198
#> gene_56   13.35303  13.41355  13.47664  12.94913  13.50268  13.18867
#> gene_57   13.32529  13.02856  13.13564  13.33181  13.24464  13.34831
#> gene_58   13.23871  13.33338  13.57448  13.33181  13.51506  13.06036
#> gene_59   12.74738  13.11101  13.28762  13.26002  13.13659  13.21904
#> gene_60   13.28265  13.23386  13.16734  13.30352  13.10417  13.36198
#> gene_61   13.28265  13.14272  13.24368  13.13718  13.12047  13.06036
#> gene_62   13.44613  13.26300  13.18294  13.34575  13.25943  13.17324
#> gene_63   13.31122  13.34706  13.50173  13.16889  13.43912  13.14188
#> gene_64   13.31122  13.29157  13.16734  13.40019  13.41289  13.04348
#> gene_65   13.19339  13.46462  13.42511  13.46547  13.15253  13.37552
#> gene_66   13.25351  13.26300  13.30198  13.18448  13.39960  13.45423
#> gene_67   13.42014  13.12695  13.19836  13.05473  13.33122  13.15764
#> gene_68   13.04821  13.40049  13.34420  13.24523  13.53952  13.42847
#> gene_69   13.36671  13.27735  13.30198  13.30352  13.25943  13.29228
#> gene_70   13.50914  13.11101  13.22874  13.12106  13.15253  13.37552
#> gene_71   13.42014  13.24850  13.13564  13.40019  13.37263  13.24878
#> gene_72   13.19339  13.30564  13.13564  13.30352  13.43912  13.33450
#> gene_73   13.28265  13.21906  13.52639  12.81529  13.47759  13.00914
#> gene_74   13.38025  13.17374  13.22874  13.05473  13.61048  13.10982
#> gene_75   13.14660  13.41355  13.30198  13.28917  13.15253  13.18867
#> gene_76   13.45896  13.17374  13.18294  13.27467  13.30293  13.23398
#> gene_77   13.01386  13.33338  13.13564  13.33181  13.18389  13.29228
#> gene_78   13.31122  13.29157  13.24368  13.47818  13.25943  13.59982
#> gene_79   13.14660  13.21906  13.46393  13.31773  13.18389  13.18867
#> gene_80   13.08176  13.27735  13.28762  13.24523  13.46488  13.29228
#> gene_81   13.20866  13.20411  13.30198  13.23028  13.27408  13.20393
#> gene_82   13.19339  13.14272  13.45111  13.23028  13.15253  13.27792
#> gene_83   13.11455  13.21906  13.19836  13.41348  13.37263  13.33450
#> gene_84   13.22376  13.23386  13.31619  13.13718  12.96669  13.45423
#> gene_85   13.28265  13.15831  13.38522  13.49078  13.30293  13.44141
#> gene_86   13.26815  13.60780  13.41194  13.23028  13.27408  13.23398
#> gene_87   13.43320  13.06211  12.91060  13.31773  13.71077  13.20393
#> gene_88   13.26815  13.06211  13.45111  13.35955  13.38618  13.26343
#> gene_89   13.26815  12.88598  13.27312  13.45265  13.35896  13.52886
#> gene_90   13.33923  13.52601  13.08673  13.24523  13.31714  13.30649
#> gene_91   13.01386  13.23386  13.39864  13.33181  13.08769  13.41541
#> gene_92   13.35303  13.40049  13.43817  13.28917  13.39960  13.40224
#> gene_93   13.29701  13.30564  13.07006  13.34575  13.33122  12.99165
#> gene_94   13.29701  13.20411  13.48924  13.45265  13.30293  13.20393
#> gene_95   13.31122  13.37402  13.18294  13.12106  13.39960  13.23398
#> gene_96   13.48427  13.20411  13.34420  13.08828  13.35896  13.41541
#> gene_97   13.45896  13.24850  13.22874  13.30352  13.39960  13.21904
#> gene_98   13.29701  13.42648  13.52639  13.35955  13.07101  13.36198
#> gene_99   13.28265  13.09490  13.31619  13.16889  13.35896  13.38894
#> gene_100  13.29701  13.41355  13.11952  13.43971  13.39960  13.40224
#>